Identification and utilization of two important transporters: SgvT1 and SgvT2, for griseoviridin and viridogrisein biosynthesis in Streptomyces griseoviridis

Abstract Background Griseoviridin (GV) and viridogrisein (VG, also referred as etamycin), both biosynthesized by a distinct 105 kb biosynthetic gene cluster (BGC) in Streptomyces griseoviridis NRRL 2427, are a pair of synergistic streptogramin antibiotics and very important in treating infections of...

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Hlavní autoři:	Yunchang Xie, Junying Ma, Xiangjing Qin, Qinglian Li, Jianhua Ju
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2017-10-01
Edice:	Microbial Cell Factories
Témata:	Metabolite transporter SgvT1 SgvT2 Griseoviridin Viridogrisein Streptogramin
On-line přístup:	http://link.springer.com/article/10.1186/s12934-017-0792-8
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