Human umbilical cord mesenchymal stem cell-derived exosomes repair IBD by activating the SIRT1-FXR pathway in macrophages

Abstract Background Inflammatory bowel disease (IBD), a chronic immune disorder, has increasing global incidence and poor treatment outcome. Abnormal macrophage function is implicated in the pathophysiology of IBD. In this study, we investigated the mechanism by which human umbilical cord mesenchyma...

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מידע ביבליוגרפי

Principais autores:	Mengjiao Zhou, Bing Pei, Peipei Cai, Chengxue Yi, Francis Atim Akanyibah, Changkun Lyu, Fei Mao
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-05-01
סדרה:	Stem Cell Research & Therapy
נושאים:	hucMSC-Ex Macrophage SIRT1-FXR pathway NLRP3 inflammasome IBD
גישה מקוונת:	https://doi.org/10.1186/s13287-025-04365-8
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!