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Identification of plasmid-mediated tigecycline resistance tet(x4) and New Delhi metallo-β-lactamase (NDM) in an Escherichia coli isolate from Canada

ABSTRACT Rapid spread of carbapenemase-producing Enterobacterales is a global health threat for which tigecycline is one of the few remaining therapeutic options. Resistance by tet(x4) is particularly worrisome, given its presence on mobile genetic elements. Here we report on a tigecycline-resistant...

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Autori principali: Laura F. Mataseje, Nicole Lerminiaux, Allison McGeer, Jennie Johnstone, Susan Poutanen, Erin McGill, Yves Longtin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2025-11-01
Serie:Microbiology Spectrum
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Accesso online:https://journals.asm.org/doi/10.1128/spectrum.00976-25
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