Metabolomic Analysis of Lytic KSHV Infection: Induced Host Nucleotide Metabolism Is Required for Infectious Virus Production

Kaposi’s Sarcoma Herpesvirus (KSHV) is the etiological agent of Kaposi’s Sarcoma (KS), which induces metabolic stress in infected host cells. KSHV reprograms host metabolic pathways for efficient viral replication and infectious virion production. Here, we report a time-course global metabolomics st...

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Autori principali:	Fatima Hisam, Emma A. Winn, Spandan Mukherjee, Savannah E. Price, Yennifer A. Gaspar, Claire Wang, Hamid R. Baniasadi, Tracie Delgado, Erica L. Sanchez
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-08-01
Serie:	Viruses
Soggetti:	Kaposi’s Sarcoma Herpesvirus (KSHV) Kaposi’s Sarcoma (KS) metabolomics methotrexate (MTX) nucleotide metabolism lytic replication
Accesso online:	https://www.mdpi.com/1999-4915/18/8/877
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