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Celastrol targets CKB-mediated futile creatine cycle in human brown adipocytes thermogenesis

Celastrol is widely recognized as one of the most potent anti-obesity agents, and its ability to promote adipocyte thermogenesis is thought to be a key mechanism. However, the precise molecular targets through which celastrol modulates thermogenesis in human adipocytes remain unclear. In this study,...

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Principais autores: Jingyi Ni, Baicheng Wang, Xinyue Liu, Rui Yin, Jinlin Tang, Siyu Hua, Xiaoxiao Zhang, Yangyang Wu, Shihu Zhang, Chenbo Ji
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-06-01
Series:Metabolism Open
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2589936825000155
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