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The expanding role of the receptor tyrosine kinase MET as a therapeutic target in non-small cell lung cancer

Summary: Aberrant regulation of MET receptor tyrosine kinase activity is a frequent event in non-small cell lung cancer (NSCLC), even though the frequency of oncogenic driver mutations of MET is low. Our discovery of oncogenic MET exon 14 skipping mutations, the characterization of the first prototy...

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Principais autores: Martin Sattler, Ravi Salgia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-03-01
coleção:Cell Reports Medicine
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666379125000564
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