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Down-regulation of Notch1 inhibits proliferation and induces apoptosis of fibroblasts from pathological scars

Objective To investigate the effect of down-regulation of Notch1 expression mediated by lentivirus on the activation of caspase-9 and mitochondrial membrane potential of fibroblast from pathological scars(PSF). Methods PSFs were isolated and cultured and then infected by Notch1 siRNA lentivirus and...

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Autor principal: SU Jiang-wei, YU Hui, DU Kun, WANG Jie, LIU Lin, CAI Jian
Format: Artigo
Idioma:Chinês
Publicat: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-03-01
Col·lecció:Jichu yixue yu linchuang
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Accés en línia:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190423.pdf
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