Limited Predictive Utility of Baseline Peripheral Blood Bulk Transcriptomics for Influenza Vaccine Responsiveness in Older Adults

<b>Background:</b> Older adults face increased risks of influenza infection and related complications due to declining immunity and reduced vaccine responsiveness. Despite widespread vaccination, only 30–40% mount immune response due to immunosenescence. However, no biomarkers exist to identify pote...

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Principais autores:	Thomas Boissiere-O’Neill, Sriganesh Srihari, Laurence Macia
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2025-12-01
叢編:	Vaccines
主題:	influenza vaccine elderly transcriptomics PBMC immunosenescence
在線閱讀:	https://www.mdpi.com/2076-393X/14/1/12
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