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Elevation of hilar mossy cell activity suppresses hippocampal excitability and avoidance behavior

Summary: Modulation of hippocampal dentate gyrus (DG) excitability regulates anxiety. In the DG, glutamatergic mossy cells (MCs) receive the excitatory drive from principal granule cells (GCs) and mediate the feedback excitation and inhibition of GCs. However, the circuit mechanism by which MCs regu...

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Autori principali: Kai-Yi Wang, Jei-Wei Wu, Jen-Kun Cheng, Chun-Chung Chen, Wai-Yi Wong, Robert G. Averkin, Gábor Tamás, Kazu Nakazawa, Cheng-Chang Lien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021-09-01
Serie:Cell Reports
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124721011499
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