Chemoresistance to Valproate Treatment of Bovine Leukemia Virus-Infected Sheep; Identification of Improved HDAC Inhibitors

We previously proved that a histone deacetylase inhibitor (valproate, VPA) decreases the number of leukemic cells in bovine leukemia virus (BLV)-infected sheep. Here, we characterize the mechanisms initiated upon interruption of treatment. We observed that VPA treatment is followed by a decrease of...

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Detalhes bibliográficos

Principais autores:	Nicolas Gillet, Fabian Vandermeers, Alix de Brogniez, Arnaud Florins, Annamaria Nigro, Carole François, Amel-Baya Bouzar, Olivier Verlaeten, Eric Stern, Didier M. Lambert, Johan Wouters, Luc Willems
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2012-10-01
Colecção:	Pathogens
Assuntos:	BLV HDAC inhibitor leukemia HTLV
Acesso em linha:	http://www.mdpi.com/2076-0817/1/2/65
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