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Behavioral and Prefrontal Circuit Deficits in a Newly Developed Setbp1 Haploinsufficiency Mouse Model

Background: SET binding protein 1 (SETBP1) regulates the cell cycle, gene transcription, and other vital intracellular processes. SETBP1 loss-of-function variants cause the neurodevelopmental disorders SETBP1-haploinsufficiency disorder and SETBP1-related disorders (SETBP1-HD and SETBP1-RD), which a...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: MacKenzie A. Howard, Mendee A. Geist, Gregory J. Ordemann, Alena Kizimenko, Dominic M. Balice, F. Isaac Guillén, Emmanuella Bassey, Polina Lyuboslavsky, Audrey C. Brumback
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2026-03-01
Rangatū:Biological Psychiatry Global Open Science
Ngā marau:
Attention-deficit/hyperactivity disorder
Autism spectrum disorder
Behavior
Electrophysiology
Neurodevelopmental disorder
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2667174325002204
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