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c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases

Our ability to learn and remember depends on the active formation, remodeling, and elimination of synapses. Thus, the development and growth of synapses as well as their weakening and elimination are essential for neuronal rewiring. The structural reorganization of synaptic complexes, changes in act...

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Автори: Daniela A Gutiérrez, América Chandía-Cristi, María José Yáñez, Silvana Zanlungo, Alejandra R Álvarez
Формат: Artigo
Мова:Inglês
Опубліковано: Wolters Kluwer Medknow Publications 2023-01-01
Серія:Neural Regeneration Research
Предмети:
actin cytoskeleton; activity-dependent plasticity; alzheimer’s disease; c-abl; dendritic spines; learning; synapse; synaptic plasticity; transcription; tyrosine kinase
Онлайн доступ:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=2;spage=237;epage=243;aulast=Gutiérrez
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