Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins

Objective Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme, that has been implicated as a biomarker of cardiovascular risk in patients with rheumatoid arthritis (RA). We aimed to investigate how different biologic therapies affect levels of PON1 and oxylipins.Methods 1213 a...

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Bibliografische Detailangaben
Hauptverfasser:	Jeffrey R Curtis, Jennifer Wang, Joel M Kremer, Srinivasa T Reddy, Dimitrios A Pappas, Christina Charles-Schoeman, David A Elashoff, Rong Guo, Amir A Razmjou, Ani Shahbazian, David Meriwether, Dawoud Sulaiman, Ellen O'Connor
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMJ Publishing Group 2024-10-01
Schriftenreihe:	RMD Open
Online-Zugang:	https://rmdopen.bmj.com/content/10/4/e004829.full
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Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins

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