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Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

Nonmusclemyosin 2 (NM-2) powers cell motility and tissue morphogenesis by assembling into bipolar filaments that interact with actin. Although the enzymatic properties of purified NM-2 motor fragments have been determined, the emergent properties of filament ensembles are unknown. Using single myosi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Luca Melli, Neil Billington, Sara A Sun, Jonathan E Bird, Attila Nagy, Thomas B Friedman, Yasuharu Takagi, James R Sellers
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2018-02-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/32871
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