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Analytical quality by design based on design space in reversed-phase-high performance liquid chromatography analysis for simultaneous estimation of metformin, linagliptin and empagliflozin

Employing the Quality by Design paradigm through this work helped conclude the method operable design region for optimizing the high performance liquid chromatography (HPLC) assay using Design of Experiments and response surface methodology to obtain a good resolution and determination of all analys...

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Principais autores: Aya A. Marie, Mohamed M. Salim, Amira H. Kamal, Sherin F. Hammad, Mahmoud M. Elkhoudary
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2022-06-01
Serier:Royal Society Open Science
Fag:
analytical quality by design
ATP
metformin
linagliptin
empagliflozin
human plasma
Online adgang:https://royalsocietypublishing.org/doi/10.1098/rsos.220215
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