Polycystin-1 Interacting Protein-1 (CU062) Interacts with the Ectodomain of Polycystin-1 (PC1)

The <i>PKD1</i> gene, encoding protein polycystin-1 (PC1), is responsible for 85% of cases of autosomal dominant polycystic kidney disease (ADPKD). PC1 has been shown to be present in urinary exosome−like vesicles (PKD−ELVs) and lowered in individuals with germline <i>PKD1</i> mutations. A label−fre...

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Principais autores:	Wendy A. Lea, Thomas Winklhofer, Lesya Zelenchuk, Madhulika Sharma, Jessica Rossol-Allison, Timothy A. Fields, Gail Reif, James P. Calvet, Jason L. Bakeberg, Darren P. Wallace, Christopher J. Ward
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2023-08-01
叢編:	Cells
主題:	polycystin-2 autosomal dominant polycystic kidney disease (ADPKD) collecting duct proximal tubule C21orf62 migrasomes
在線閱讀:	https://www.mdpi.com/2073-4409/12/17/2166
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