IRF4 contributes to chemoresistance in IGH::BCL2‐positive diffuse large B‐cell lymphomas by mediating BCL2‐induced SOX9 expression

Abstract Background Diffuse large B‐cell lymphoma (DLBCL), an aggressive type of non‐Hodgkin's lymphoma, has a high relapse/refractory rate. We previously identified sex‐determining region Y (SRY)‐box transcription factor (SOX9) as a transcription factor that serves as a prognostic biomarker, partic...

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Detalhes bibliográficos

Principais autores:	Yirong Zhang, Zizhen Xu, Ruixin Sun, Yixuan Gao, Innocent Agida, Kasimujiang Aximujiang, Lin Yuan, Jiao Ma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-05-01
coleção:	Clinical and Translational Medicine
Assuntos:	BCL2 chemoresistance IGH::BCL2‐positive DLBCL IRF4 SOX9
Acesso em linha:	https://doi.org/10.1002/ctm2.70336
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