Polygenic Risk Score Improves Cataract Prediction in East Asian Population

Cataracts, characterized by crystalline lens opacities in human eyes, is the leading cause of blindness globally. Due to its multifactorial complexity, the molecular mechanisms remain poorly understood. Larger cohorts of genome-wide association studies (GWAS) are needed to investigate cataracts’ gen...

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主要な著者:	Chih-Chien Hsu, Hao-Kai Chuang, Yu-Jer Hsiao, Yuan-Chi Teng, Pin-Hsuan Chiang, Yu-Jun Wang, Ting-Yi Lin, Ping-Hsing Tsai, Chang-Chi Weng, Tai-Chi Lin, De-Kuang Hwang, Ai-Ru Hsieh
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-08-01
シリーズ:	Biomedicines
主題:	cataract genome-wide association studies polygenic risk score Asian population biobank retrospective study
オンライン･アクセス:	https://www.mdpi.com/2227-9059/10/8/1920
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