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Identification of a Biosynthetic Gene Cluster Responsible for the Production of a New Pyrrolopyrimidine Natural Product—Huimycin

Pyrrolopyrimidines are an important class of natural products with a broad spectrum of biological activities, including antibacterial, antifungal, antiviral, anticancer or anti-inflammatory. Here, we present the identification of a biosynthetic gene cluster from the rare actinomycete strain <i>Kutzn...

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Principais autores: Hui Shuai, Maksym Myronovskyi, Suvd Nadmid, Andriy Luzhetskyy
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-07-01
Serier:Biomolecules
Fag:
kutzneria
nucleoside
pyrrolopyrimidines
secondary metabolites
heterologous expression
Online adgang:https://www.mdpi.com/2218-273X/10/7/1074
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