Charge pattern matching as a ‘fuzzy’ mode of molecular recognition for the functional phase separations of intrinsically disordered proteins

Biologically functional liquid–liquid phase separation of intrinsically disordered proteins (IDPs) is driven by interactions encoded by their amino acid sequences. Little is currently known about the molecular recognition mechanisms for distributing different IDP sequences into various cellular memb...

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Hlavní autoři:	Yi-Hsuan Lin, Jacob P Brady, Julie D Forman-Kay, Hue Sun Chan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	IOP Publishing 2017-01-01
Edice:	New Journal of Physics
Témata:	random phase approximation polymer theory liquid–liquid phase separation membraneless organelles effective medium approximations
On-line přístup:	https://doi.org/10.1088/1367-2630/aa9369
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