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Metabolic abnormalities exacerbate Sjögren’s syndrome by and is associated with increased the population of interleukin–17–producing cells in NOD/ShiLtJ mice

Abstract Background Sjögren’s syndrome (SS) is an autoimmune disease mediated by lymphocytic infiltration into exocrine glands, resulting in progressive lacrimal and salivary destruction and dysfunctional glandular secretion. Metabolic syndrome influences the immune system. To investigate its relati...

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Principais autores: Sun-Hee Hwang, Jin-Sil Park, SeungCheon Yang, Kyung-Ah Jung, JeongWon Choi, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-05-01
Serier:Journal of Translational Medicine
Fag:
Sjögren’s syndrome
Type 1 diabetes
Interleukin-17
IL–17–producing T cell
IL–17–producing B cell
Online adgang:http://link.springer.com/article/10.1186/s12967-020-02343-7
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