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Knockout of Dectin-1 does not modify disease onset or progression in a MATR3 S85C knock-in mouse model of ALS

Microglia have been increasingly implicated in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Dectin-1, encoded by the Clec7a gene, is highly upregulated in a specific microglial response state called disease-associated microglia (DAM) in various neurodegenerative conditi...

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Bibliográfalaš dieđut
Váldodahkkit: Justin You, Katarina Maksimovic, Mark N. Metri, Anneka Schoeppe, Karin Chen, Jooyun Lee, Jhune Rizsan Santos, Mohieldin M.M. Youssef, Michael W. Salter, Jeehye Park
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2024-09-01
Ráidu:Heliyon
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2405844024139576
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