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In silico drug-likeness /ADMET prediction and molecular docking studies on key chemical constituents of Crataegus Azarolus L. for preventing cardiovascular disease

Introduction: Elevated plasma LDL cholesterol levels play a crucial role in cardiovascular disease development. Squalene synthase (SQS), a regulatory enzyme in cholesterol biosynthesis, is a target for controlling hypercholesterolemia. Traditional medicine recommends Crataegus Azarolus L. for heart-...

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Hlavní autoři: Azizeh Asadzadeh, Azam Moshfegh, Fatemeh Shams Moattar
Médium: Artigo
Jazyk:Inglês
Vydáno: Ilam University of Medical Sciences 2023-06-01
Edice:Journal of Basic Research in Medical Sciences
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On-line přístup:http://jbrms.medilam.ac.ir/article-1-776-en.pdf
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