How are missing data in covariates handled in observational time-to-event studies in oncology? A systematic review

Abstract Background Missing data in covariates can result in biased estimates and loss of power to detect associations. It can also lead to other challenges in time-to-event analyses including the handling of time-varying effects of covariates, selection of covariates and their flexible modelling. T...

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Главные авторы:	Orlagh U. Carroll, Tim P. Morris, Ruth H. Keogh
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2020-05-01
Серии:	BMC Medical Research Methodology
Предметы:	Missing data Time-to-event Observational studies Survival Epidemiology Oncology
Online-ссылка:	http://link.springer.com/article/10.1186/s12874-020-01018-7
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