Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Abstract Acute lymphoblastic leukemia (ALL) is the most common malignant hematological diseases in children. An immunosuppressive microenvironment, particularly regulatory T cell (Treg) infiltration, has been documented to be highly associated with childhood ALL. This present study, based on genetic...

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Библиографические подробности

Главные авторы:	Yaping Wang, Xiaopeng Ma, Jie Huang, Xiaoyun Yang, Meiyun Kang, Xiaoyan Sun, Huimin Li, Yijun Wu, Heng Zhang, Yuting Zhu, Yao Xue, Yongjun Fang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2022-05-01
Серии:	Cell Death and Disease
Online-ссылка:	https://doi.org/10.1038/s41419-022-04873-y
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