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Molecular Basis for the Selectivity of DHA and EPA in Sudlow’s Drug Binding Sites in Human Serum Albumin with the Combined Use of NMR and Docking Calculations

Medium- and long-chain saturated and unsaturated free fatty acids (FFAs) are known to bind to human serum albumin (HSA), the main plasma carrier protein. Atomic-level structural data regarding the binding mode in Sudlow’s sites I (FA7) and II (FA4, FA3) of the polyunsaturated ω-3 fatty acids docosah...

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Detaylı Bibliyografya
Asıl Yazarlar: Eleni Alexandri, Themistoklis Venianakis, Alexandra Primikyri, Georgios Papamokos, Ioannis P. Gerothanassis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2023-04-01
Seri Bilgileri:Molecules
Konular:
Online Erişim:https://www.mdpi.com/1420-3049/28/9/3724
Etiketler: Etiketle
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