Cross-neutralizing antibody against emerging Omicron subvariants of SARS-CoV-2 in infection-naïve individuals with homologous BNT162b2 or BNT162b2(WT + BA.4/5) bivalent booster vaccination

Abstract Since the emergence of SARS-CoV-2, different variants and subvariants successively emerged to dominate global virus circulation as a result of immune evasion, replication fitness or both. COVID-19 vaccines continue to be updated in response to the emergence of antigenically divergent viruse...

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Hauptverfasser:	Samuel M.S. Cheng, Chris K.P. Mok, John K.C. Li, Ken K.P. Chan, Kristine S. Luk, Ben H.W. Lee, Haogao Gu, Karl C.K. Chan, Leo C.H. Tsang, Karen Y.S. Yiu, Ken K.C. Ling, Yun Sang Tang, Leo L.H. Luk, Jennifer K.M. Yu, Andrew Pekosz, Richard J. Webby, Benjamin J. Cowling, David S.C. Hui, Malik Peiris
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-03-01
Schriftenreihe:	Virology Journal
Schlagworte:	SARS-CoV-2 Omicron subvariant Immune evasion Neutralization Antigenic cartography Bivalent RNA vaccine
Online-Zugang:	https://doi.org/10.1186/s12985-024-02335-9
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