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Genetic atlas of plasma metabolome across 40 human common diseases: mapping causal metabolites to disease risk

Abstract Background Metabolites are closely linked to individual health and disease conditions. Identifying genetic factors influencing metabolite levels in specific diseases can enhance our understanding of disease etiology and informing precision medicine. This study aims to characterize the genet...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Yanmin Li, Yimin Cai, Qianying Ma, Xiaojun Yang, Chunyi He, Ying Xu, Ming Zhang, Zequn Lu, Can Chen, Caibo Ning, Bo Liu, Yongchang Wei, Xiangpan Li, Meng Jin, Xu Zhu, Bin Li, Ying Zhu, Chaoqun Huang, Xiaoping Miao, Jianbo Tian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-11-01
Seri Bilgileri:Genome Medicine
Konular:
Metabolomic
Genetic variants
metQTLs
Mendelian randomization
Polygenic risk score
Online Erişim:https://doi.org/10.1186/s13073-025-01578-7
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