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Randomized controlled trial of intermittent hypoxia in Parkinson’s disease: study rationale and protocol

Abstract Background Parkinson’s disease (PD) is a neurodegenerative disease for which no disease-modifying therapies exist. Preclinical and clinical evidence suggest that repeated exposure to intermittent hypoxia might have short- and long-term benefits in PD. In a previous exploratory phase I trial...

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Principais autores: Jules M. Janssen Daalen, Marjan J. Meinders, Soania Mathur, Hieronymus W.H. van Hees, Philip N. Ainslie, Dick H.J. Thijssen, Bastiaan R. Bloem
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-06-01
Serier:BMC Neurology
Fag:
Parkinson's disease
Disease modification
Disease-modifying tria
Hypoxia
hypoxic conditioning
Mitochondrial dysfunction
Online adgang:https://doi.org/10.1186/s12883-024-03702-3
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