Lower hippocampal volume partly mediates the association between rs6859 in the NECTIN2 gene and Alzheimer’s disease: new findings from causal mediation analysis of ADNI data
IntroductionAlzheimer’s disease (AD) is a complex disorder influenced by many factors. The rs6859 polymorphism in the NECTIN2 gene has been consistently linked to AD risk. The NECTIN2 is involved in vulnerability to infections, which could contribute to neurodegeneration. We hypothesized that hippoc...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2026-02-01
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| Series: | Frontiers in Aging Neuroscience |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fnagi.2026.1715773/full |
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