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Deciphering the immune-metabolic nexus in sepsis: a single-cell sequencing analysis of neutrophil heterogeneity and risk stratification

BackgroundMetabolic dysregulation following sepsis can significantly compromise patient prognosis by altering immune-inflammatory responses. Despite its clinical relevance, the exact mechanisms of this perturbation are not yet fully understood.MethodsSingle-cell RNA sequencing (scRNA-seq) was utiliz...

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Bibliografski detalji
Glavni autori: Shaoxiong Jin, Huazhi Zhang, Qingjiang Lin, Jinfeng Yang, Rongyao Zeng, Zebo Xu, Wendong Sun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2024-07-01
Serija:Frontiers in Immunology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1398719/full
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