Mitochondrial aberrations in systemic lupus erythematosus pathogenesis: Insights and therapeutic implications

Abstract Systemic lupus erythematosus (SLE), a chronic autoimmune disease, is marked by impaired immune tolerance and heightened activity in both innate and adaptive immune systems. Hallmarks of SLE include elevated type I interferons and autoantibody production, though the exact causes of SLE remai...

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Autores principales:	Haoguang Li, Lu Zhou, Wei Zhou, Xiuling Zhang, Jingjing Shang, Xueqin Feng, Le Yu, Jie Fan, Jie Ren, Rongwei Zhang, Xinwang Duan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2024-06-01
Colección:	Rheumatology & Autoimmunity
Materias:	mitochondrial dysfunctions mitophagy oxidative stress systemic lupus erythematosus therapeutic potential
Acceso en línea:	https://doi.org/10.1002/rai2.12119
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