A mini review of small-molecule inhibitors targeting palmitoyltransferases

Palmitoylation occurs when fatty acids (such as palmitic acid) create covalent bonds between cysteine, serine, threonine, or other residues in proteins. The downstream effect of palmitoylation depends on the protein being palmitoylated because its blockage can render the protein useless in terms of...

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Autors principals:	Xiaotong Hu, Xinyue Zhu, Wei Yu, Yiwen Zhang, Kan Yang, Zhenming Liu, Xiaoqiang Qiao, Yali Song
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-08-01
Col·lecció:	European Journal of Medicinal Chemistry Reports
Matèries:	Inhibitors Serine palmitoyltransferase Carnitine palmitoyltransferase Protein palmitoyltransferase
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2772417422000139
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