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C-reactive protein-complement factor H axis as a biomarker of activity in early and intermediate age-related macular degeneration

PurposeTo determine and compare the serum levels of complement Factor H (FH), monomeric C-Reactive Protein (mCRP) and pentameric C-Reactive protein (pCRP) in patients with age-related macular degeneration (AMD) and to correlate them with clinical, structural and functional parameters.MethodsCross-se...

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Principais autores: Lena Giralt, Marc Figueras-Roca, Beatriz De Luis Eguileor, Barbara Romero, Javier Zarranz-Ventura, Socorro Alforja, Francisca Santiago, Jennifer Bolaños, Francisco Lozano, Marina Dotti-Boada, Anna Sala-Puigdollers, Paula Dura, Jordi Izquierdo-Serra, Oliver Valero, Alfredo Adan, Alex Fonollosa, Blanca Molins
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-04-01
coleção:Frontiers in Immunology
Assuntos:
age-related macular degeneration
inflammation
complement factor H
C-reactive protein
retina
biomarker
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330913/full
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