ACE mRNA (Additional Chimeric Element incorporated IVT mRNA) for Enhancing Protein Expression by Modulating Immunogenicity

Abstract The development of in vitro transcribed mRNA (IVT mRNA)‐based therapeutics/vaccines depends on the management of IVT mRNA immunogenicity. IVT mRNA, which is used for intracellular protein translation, often triggers unwanted immune responses, interfering with protein expression and leading...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Sora Son, Minsa Park, Jin Kim, Kyuri Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-05-01
coleção:	Advanced Science
Assuntos:	immunogenicity mRNA therapeutics protein expression RNA structure
Acesso em linha:	https://doi.org/10.1002/advs.202307541
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!