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Experimental validation that human microbiome phages use alternative genetic coding

Previous bioinformatic analyses have indicated that bacteriophages can use genetic codes different from those of their host bacteria. Here, Peters et al. use metaproteomics to provide experimental evidence of reassignment of stop codon TAG to glutamine in phages found in the human gut microbiome.

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Détails bibliographiques
Auteurs principaux: Samantha L. Peters, Adair L. Borges, Richard J. Giannone, Michael J. Morowitz, Jillian F. Banfield, Robert L. Hettich
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2022-09-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-022-32979-6
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