Non-invasive bioelectrical therapy suppresses retinal neovascularization by modulating cellular metabolism and inflammation

Abstract Background Pathological retinal neovascularization, a major cause of blindness, occurs in conditions such as age-related macular degeneration (AMD) and diabetic retinopathy (DR). Microglial activation and chronic neuroinflammation play critical roles in disease progression by promoting vasc...

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Principais autores:	Anton Lennikov, Menglu Yang, Farris Elzaridi, Daisy Y. Shu, Zhengping Hu, William P. Miller, Matthijs Tsonas, Lu Huang, Christina Yen, Karen Chang, Julie Chen, Aruvi Vijikumar, Ajay Ashok, Kin-Sang Cho, Magali Saint Geniez, Darlene A. Dartt, Dong Feng Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-11-01
Series:	Cell Communication and Signaling
Assuntos:	Angiogenesis Electrical stimulation Microglia Retinal endothelial cells Mitochondria Ca2+ signaling
Acceso en liña:	https://doi.org/10.1186/s12964-025-02451-1
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