Steering CAR T cells to distinguish friend from foe
CD19-specific chimeric antigen receptor (CAR)+ T cells have demonstrated clinical efficacy and long-lasting remissions, concomitant with tolerable normal B-cell aplasia. However, many tumor-associated antigens (TAAs) are expressed on normal tissues, the destruction of which would lead to intolerable...
Bewaard in:
| Hoofdauteurs: | , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis Group
2019-10-01
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| Reeks: | OncoImmunology |
| Onderwerpen: | |
| Online toegang: | http://dx.doi.org/10.1080/2162402X.2016.1271857 |
| Tags: |
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