Dietary gangliosides rescue GM3 synthase deficiency outcomes in mice accompanied by neurogenesis in the hippocampus

Ganglioside GM3 synthase is a key enzyme involved in the biosynthesis of gangliosides. GM3 synthase deficiency (GM3SD) causes an absence of GM3 and all downstream biosynthetic derivatives, including all the a-, b-, c-series gangliosides, commonly found in neural tissues. The affected individuals man...

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Detalhes bibliográficos

Principais autores:	Jin-ichi Inokuchi, Shinji Go, Akemi Suzuki, Osamu Nakagawasai, Takayo Odaira-Satoh, Lucas Veillon, Takahiro Nitta, Paul McJarrow, Hirotaka Kanoh, Kei-ichiro Inamori, Koichi Tan-No, Michael Collett
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-07-01
Colecção:	Frontiers in Neuroscience
Assuntos:	GM3 synthase deficiency milk gangliosides GM3 GD3 oral supplementation neurogenesis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1387221/full
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