A chikungunya virus-like particle vaccine reduces chikungunya disease in cynomolgus macaques and protection is mediated by antibody transferred from vaccinated humans

Abstract Chikungunya virus (CHIKV) causes periodic outbreaks and is endemic in more than 110 countries. VIMKUNYA, a CHIKV virus-like particle (CHIKV VLP) vaccine, was recently approved by regulators in the United States, European Union, and United Kingdom. Efficacy of VIMKUNYA in endemic settings is...

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Principais autores:	Lark L. Coffey, Katherine J. Olstad, J. Rachel Reader, Amir Ardeshir, Christopher M. Weiss, Jennifer K. Watanabe, Jodie L. Usachenko, JoAnn Yee, Anil Singapuri, Zhong Min Ma, Alexis Mackiewicz, Rebecca Sammak, Jackson Stuart, Ramya Immareddy, Ravi Anantha, Kelly L. Warfield, Darly Manayani, Jeff Alexander, Jonathan Smith, Lo Vang, Christopher M. Cirimotich, Cassandra O’Connor, Ben Guenther, Nhuxuan Ho, Christopher S. Morello, Jason Mendy, Jason S. Richardson, Koen K. A. Van Rompay
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2026-03-01
Serija:	npj Vaccines
Online dostop:	https://doi.org/10.1038/s41541-026-01413-z
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