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HIV-1 env gene mutations outside the targeting probe affects IPDA efficiency

Summary: The intact proviral DNA assay (IPDA) based on droplet digital PCR was developed to identify intact proviral DNA and quantify HIV-1 latency reservoirs in patients infected with HIV-1. However, the genetic characteristics of different HIV-1 subtypes are non-consistent due to their high mutati...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Zehua Zhou, Xinyu Zhang, Meiyu Wang, Fei Jiang, Jincheng Tong, Jianhui Nie, Chenyan Zhao, Haifa Zheng, Zhen Zhang, Penghui Shi, Weiguang Fan, Youchun Wang, Weijin Huang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-06-01
Schriftenreihe:iScience
Schlagworte:
Virology
Methodology in biological sciences
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004224011635
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