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Stress granules in the spinal muscular atrophy and amyotrophic lateral sclerosis: The correlation and promising therapy

Increasing genetic and biochemical evidence has broadened our view of the pathomechanisms that lead to Spinal muscular atrophy (SMA) and Amyotrophic lateral sclerosis (ALS), two fatal neurodegenerative diseases with similar symptoms and causes. Stress granules are dynamic cytosolic storage hubs for...

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Principais autores: LiDan Hu, Shanshan Mao, Li Lin, Guannan Bai, Bingjie Liu, Jianhua Mao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-08-01
Serier:Neurobiology of Disease
Fag:
Stress granules
Amyotrophic lateral sclerosis
Spinal muscular atrophy
RNA binding proteins
Drug
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996122001413
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