Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation

Summary: Formation of synapses between motor neurons and muscles is initiated by clustering of acetylcholine receptors (AChRs) in the center of muscle fibers prior to nerve arrival. This AChR patterning is considered to be critically dependent on calcium influx through L-type channels (CaV1.1). Usin...

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Detalhes bibliográficos

Principais autores:	Mehmet Mahsum Kaplan, Nasreen Sultana, Ariane Benedetti, Gerald J. Obermair, Nina F. Linde, Symeon Papadopoulos, Anamika Dayal, Manfred Grabner, Bernhard E. Flucher
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2018-06-01
coleção:	Cell Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124718308660
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