Precision RNA interference of Smad3 and Runx2 via dual targeting nanocarriers mitigates aortic valve disease
Abstract Background Calcific aortic valve disease (CAVD) is a common malady with few treatment options other than valve replacement by surgery or transcatheter aortic valve implantation (TAVI). Endothelial-to-mesenchymal transition (EndMT) of valvular endothelial cells and osteogenic differentiation...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2026-01-01
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| Col·lecció: | Journal of Translational Medicine |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12967-026-07686-1 |
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