Differences in microRNA levels across metabo-endotypes reveal novel insights into asthma heterogeneity

Abstract Rationale We previously validated five clinically distinct asthma metabo-endotypes (mechanistically derived asthma subgroups). We hypothesize that metabo-endotype membership may be partially driven by differences in serum microRNA profiles and their influence on metabolite levels. Objective...

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Detalhes bibliográficos

Principais autores:	Rinku Sharma, Rachel S. Kelly, Kevin Mendez, Qingwen Chen, Julian Hecker, Sofina Begum, Clary Clish, Juan C. Celedón, Kelan G. Tantisira, Scott T. Weiss, Jessica Lasky-Su, Michael J. McGeachie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	Respiratory Research
Assuntos:	Asthma MicroRNAs GACRS Metabolomics Metabo-endotype
Acesso em linha:	https://doi.org/10.1186/s12931-025-03452-x
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