α2- and β2-Adrenoreceptor-Mediated Efficacy of the Atypical Antidepressant Agomelatine Combined With Gabapentin to Suppress Allodynia in Neuropathic Rats With Ligated Infraorbital or Sciatic Nerve

Previous data showed that neuropathic pain induced by mechanical lesion of peripheral nerves has specific characteristics and responds differently to alleviating drugs at cephalic versus extracephalic level. This is especially true for tricyclic antidepressants currently used for alleviating neuropa...

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Bibliografische Detailangaben

Hauptverfasser:	Saïd M’Dahoma, Matthieu Poitevin, Eric Dabala, Hugo Payan, Cecilia Gabriel, Elisabeth Mocaër, Sylvie Bourgoin, Michel Hamon
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2018-06-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	chronic constriction injury sciatic nerve infraorbital nerve neuropathic rats mechanical allodynia agomelatine
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fphar.2018.00587/full
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