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Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes.

Subpopulations of B-lymphocytes traffic to different sites and organs to provide diverse and tissue-specific functions. Here, we provide evidence that epigenetic differences confer a neuroinvasive phenotype. An EBV+ B cell lymphoma cell line (M14) with low frequency trafficking to the CNS was neuroa...

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Hoofdauteurs: Samantha S Soldan, Chenhe Su, R Jason Lamontagne, Nicholas Grams, Fang Lu, Yue Zhang, James D Gesualdi, Drew M Frase, Lois E Tolvinski, Kayla Martin, Troy E Messick, Jonathan T Fingerut, Ekaterina Koltsova, Andrew Kossenkov, Paul M Lieberman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2021-06-01
Reeks:PLoS Pathogens
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216538
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