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Biosynthesis and Biological Significances of LacdiNAc Group on <i>N</i>- and <i>O</i>-Glycans in Human Cancer Cells

An increasing number of studies have shown that the disaccharide GalNAcβ1→4GlcNAc (LacdiNAc) group bound to <i>N</i>- and <i>O</i>-glycans in glycoproteins is expressed in a variety of mammalian cells. Biosynthesis of the LacdiNAc group was well studied, and two β4-<i>N</i>-acetylgalactosaminyltrans...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kiyoko Hirano, Kiyoshi Furukawa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Biomolecules
Schlagworte:
LacdiNAc
β4-<i>N</i>-acetylgalactosaminyltransferase
tumor malignancy
epithelial-mesenchymal or mesenchymal-epithelial transition
gene therapy
Online-Zugang:https://www.mdpi.com/2218-273X/12/2/195
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