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Cochaperones convey the energy of ATP hydrolysis for directional action of Hsp90

Abstract The molecular chaperone and heat shock protein Hsp90 is part of many protein complexes in eukaryotic cells. Together with its cochaperones, Hsp90 is responsible for the maturation of hundreds of clients. Although having been investigated for decades, it still is largely unknown which compon...

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Bibliografiske detaljer
Principais autores: Leonie Vollmar, Julia Schimpf, Bianca Hermann, Thorsten Hugel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-01-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-024-44847-6
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