Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia

Abstract Background Cachexia frequently occurs in women with advanced ovarian cancer (OC), along with enhanced inflammation. Despite being responsible for one third of all cancer deaths, cachexia is generally under‐studied in OC due to a limited number of pre‐clinical animal models. We aimed to addr...

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Detalhes bibliográficos

Principais autores:	Fabrizio Pin, Rafael Barreto, Yukiko Kitase, Sumegha Mitra, Carlie E. Erne, Leah J. Novinger, Teresa A. Zimmers, Marion E. Couch, Lynda F. Bonewald, Andrea Bonetto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2018-08-01
coleção:	Journal of Cachexia, Sarcopenia and Muscle
Assuntos:	Cancer cachexia Ovarian cancer Skeletal muscle Animal model ES‐2 IL‐6
Acesso em linha:	https://doi.org/10.1002/jcsm.12311
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